2009 Request for Research Proposals
The Barth Syndrome Foundation, Inc. (BSF) and its affiliates are pleased to announce the availability of funding for research internationally on the natural history, biochemical basis, gene product function and treatment of Barth syndrome.
Background
Barth syndrome is a serious X-linked genetic condition associated with cardiomyopathy, neutropenia, skeletal muscle weakness, exercise intolerance, growth delay, and diverse biochemical abnormalities (including defects in mitochondrial metabolism and phospholipid biosynthesis). Because many clinical and biochemical abnormalities of Barth syndrome remain poorly understood, we are seeking proposals for research that will advance knowledge on any aspect of the syndrome. We are determined to find improved treatments – and ultimately a cure – for this rare and underdiagnosed disorder.
Types of Proposals Sought
We are most interested in providing “seed money” to be used by experienced investigators for the testing of initial hypotheses and collection of preliminary data leading to successful long-term funding by NIH and other major granting institutions. In addition, we are especially interested in attracting new investigators to the very interesting field of Barth syndrome research.
Funding
We anticipate awarding several one- or two-year grants of up to $40,000 each. Funds will be available as soon as the successful grant applicants have been notified.
Process
We have a simple grant process. Applications should be of 10-15 pages in length and must follow the instructions listed on the BSF website. In general terms, detailed information about the specific aims, significance, research design and methods, personnel, and budget will be required, along with evidence of application to the relevant Institutional Review Board for any work involving human subjects and the Animal Use and Protection Committee for any work involving animal subjects.
Completed proposals will be forwarded to the BSF Scientific and Medical Advisory Board (as well as to outside reviewers, in certain cases) for evaluation. Based on the recommendations of the Scientific and Medical Advisory Board, the BSF Board of Directors and those of our three international affiliates will make the final funding decisions for the grant applications.
Deadline
The deadline for submission of completed research grant applications from interested researchers is October 31, 2009. Grants will be awarded early March 2010.