Request for Applications (RFAs)

The Barth Syndrome Foundation (BSF) Research Grant Program continues to encourage basic science and clinical research on the natural history, biochemical basis, and treatment of Barth syndrome. In addition to this fundamental program, the BSF and its international affiliates are pleased to announce the availability of specific REQUEST FOR APPLICATIONS (RFAs) as part of the BSF Research Grant Program. These RFAs are in addition to the usual appeal for research grant applications on Barth syndrome. The goal of BSF´s Research Grant Program is to advance medical knowledge of the basic mechanism of the disease so as to develop more accurate diagnostic methods and improved specific therapies for children and adults affected by Barth syndrome. All applications for the 2017 cycle will be evaluated competitively against each other in the same cycle. Applicants should determine whether to apply for an Idea Grant (US $50,000 maximum for 1-2 years), or for a Development Grant (US $100,000 maximum over 2-3 years) as appropriate. All Development Grant applications and applications to the RFAs require a letter of intent (1 page maximum with due date of September 7, 2017) explaining their idea. Feedback will be provided by the Grant Review Committee of the Scientific and Medical Advisory Board.

Although BSF will consider any research proposal related to Barth syndrome, it is particularly interested in supporting research in the following areas:

  • The mechanism of neutropenia in Barth syndrome,
  • The gastrointestinal pathophysiology in Barth syndrome, and
  • The search for compounds that may improve mitochondrial performance in Barth syndrome.

Applications for any of these three areas will be accepted for both Idea Grants and Development Grants, and will be given preferential consideration in the 2017 BSF Research Grant Program cycle.

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